Evaluation of myocardial oxidative stress markers and cGMP-PKGIα signaling. All the measurements were carried out after 4 hours of reperfusion. (a) Myocardial superoxide generation, (b) myocardial malondialdehyde (MDA) contents, (c) representative blots, (d) gp91phox expression, (e) catalase expression, (f) MnSOD expression, (g) myocardial cGMP level, (h) representative blots, (i) PKGIα expression, and (j) VASP (Ser239) phosphorylation. Data are expressed as mean ± SEMn = 6 per group. @P < 0.05/@@P < 0.01vs. sham group, #P < 0.05vs. MI/R + V group, and $P < 0.05/$$P < 0.01vs. MI/R + NRG group. MI/R: myocardial ischemia-reperfusion; V: vehicle; NRG: naringenin.