Table 1.
Clinical characteristics of the study group participants
| Overall | Control subjects | AAB− FDR | AAB+ single | AAB+ multiple | Recent onset | |
|---|---|---|---|---|---|---|
| N (%) | 229 | 49 (21.4) | 61 (26.6) | 31 (13.5) | 36 (15.7) | 52 (22.7) |
| Male sex | 101 (44.1) | 20 (40.8) | 23 (37.7) | 9 (29.0) | 22 (61.1) | 27 (51.9) |
| Age (years) | 19.6 ± 10.5 | 18.4 ± 5.9 | 21.1 ± 11.7 | 28.8 ± 13.3 | 15.9 ± 10.7 | 16.2 ± 6.1 |
| Body weight (kg) | 61.0 ± 23.7 | 61.8 ± 17.8 | 63.0 ± 22.1 | 75.3 ± 31.0 | 49.9 ± 22.6 | 61.3 ± 23.0 |
| BMI | 23.2 ± 6.4 | 22.7 ± 4.8 | 23.6 ± 6.1 | 27.6 ± 8.6 | 20.0 ± 5.7 | 22.6 ± 5.9 |
| PV | 74.9 ± 31.8 | 88.2 ± 30.8 | 81.2 ± 29.8 | 89.3 ± 35.4 | 61.2 ± 28.0 | 55.7 ± 21.6 |
| RPVBW | 1.2 ± 0.4 | 1.4 ± 0.4 | 1.3 ± 0.3 | 1.2 ± 0.3 | 1.2 ± 0.2 | 0.9 ± 0.2 |
| RPVBMI | 3.2 ± 1.1 | 3.9 ± 1.1 | 3.5 ± 0.9 | 3.3 ± 1.1 | 3.0 ± 1.0 | 2.5 ± 0.2 |
| RPV-to-height ratio | 0.5 ± 0.2 | 0.5 ± 0.2 | 0.5 ± 0.2 | 0.5 ± 0.2 | 0.4 ± 0.1 | 0.3 ± 0.1 |
| Race/ethnicity | ||||||
| NH white | 177 (77.3) | 28 (57.1) | 52 (85.3) | 25 (80.7) | 29 (80.6) | 43 (82.7) |
| NH black | 11 (4.8) | 5 (10.2) | 1 (3.2) | 3 (8.3) | 2 (3.9) | |
| NH Asian | 2 (0.9) | 1 (2.0) | 1 (1.9) | |||
| NH Am. Indian, Alaska Native | — | — | — | — | — | — |
| NH Hawaiian, Pacific Islander | 1 (0.4) | 1 (2.0) | ||||
| Hispanic | 27 (11.8) | 6 (12.2) | 8 (13.1) | 4 (12.9) | 4 (11.1) | 5 (9.6) |
| NH multiple race/unknown | 11 (4.8) | 8 (16.3) | 1 (1.6) | 1 (3.2) | 1 (1.9) | |
| Laboratory tests* | ||||||
| HbA1c (%) | 5.5 ± 1.0 | 5.0 ± 0.3 | 5.1 ± 0.3 | 5.2 ± 0.3 | 5.1 ± 0.4 | 7.0 ± 1.3 |
| HbA1c (mmol/mol) | 36.8 ± 11.2 | 31.5 ± 3.6 | 32.0 ± 3.3 | 33.5 ± 3.5 | 32.6 ± 3.9 | 52.6 ± 13.9 |
| Glucose (mg/dL) | 104.0 ± 37.5 | 90.0 ± 6.0 | 93.0 ± 6.7 | 96.0 ± 8.7 | 94.7 ± 16.0 | 141.4 ± 64.3 |
| C-peptide (ng/mL) | 2.0 ± 1.2 | 2.1 ± 0.7 | 2.3 ± 1.3 | 2.5 ± 1.2 | 1.9 ± 1.2 | 1.2 ± 0.9 |
| Trypsinogen (ng/mL) | 23.9 ± 18.9 | 23.4 ± 10.0 | 25.8 ± 12.4 | 38.2 ± 40.5 | 20.0 ± 8.6 | 16.3 ± 9.9 |
Data are mean ± SD or N (%). Am. Indian, American Indian; NH, non-Hispanic.
*HbA1c (% and mmol/mol), n missing = 5; glucose, n missing = 0; C-peptide, n missing = 1; trypsinogen, exclusion of outlier n = 1 and missing for analysis = 16.