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. 2018 Nov 13;68(2):430–440. doi: 10.2337/db18-0845

Figure 4.

Figure 4

Blood glucose is not effected by knocking out NLRP3. Blood glucose levels were assessed at week 15 using the AimStrip Plus blood glucose testing system. A: Blood glucose is very significantly increased in the diabetic mouse with an NLRP3+/+ genotype. n = 27 (nondiabetic [non-diab]) and 12 (diabetic [diab]). ***P < 0.0001 by paired Student t test. B: Blood glucose is significantly elevated in the diabetic mouse with an NLRP3−/− genotype. Bars are mean ± SEM. n = 18 (nondiabetic) and 21 (diabetic). ***P < 0.0001 by Student two-tailed t test. ANOVA followed by Tukey post hoc test was also used to compare all groups. No additional significant differences were found.