Table III.
Genotype and allele frequencies of adiponectin +276G/T polymorphism within the ACL subgroups.
| ACL subgroups based on mechanism of injury, n (%) | Model 1 | Model 2 | |||||
|---|---|---|---|---|---|---|---|
| Variables | Controls, n (%) (n=95) | Non-contact sports (n=51) | Contact sports (n=47) | Adjusted ORa (95% CI) | P-value | Adjusted ORa (95% CI) | P-value |
| Genotype frequencies | |||||||
| GG | 40 (42.11) | 31 (60.78) | 26 (55.32) | 0.79 (0.36-1.79) | NS | 2.13 (1.06-4.27) | 0.031b |
| GT | 39 (41.05) | 16 (31.37) | 19 (40.43) | 1.48 (0.65-3.40) | NS | 1.52 (0.74-3.13) | NS |
| TT | 16 (16.84) | 4 (7.84) | 2 (4.26) | 0.52 (0.091-2.99) | NS | 0.42 (0.13-1.33) | NS |
| Allele frequencies | |||||||
| G | 119 (62.63) | 71 (75.53) | 78 (76.47) | 0.91 (0.47-1.76) | NS | 1.84 (1.06-3.21) | 0.029c |
| T | 71 (37.37) | 23 (24.47) | 24 (23.53) | ||||
Model 1: ACL patients with non-contact sports vs. contact sports. Model 2: Healthy controls vs. ACL patients with non-contact sports. aAdjusted for age and body mass index.
bHealthy controls vs. ACL patients with non-contact sports, GG genotype vs. TT + GT genotypes.
cHealthy controls vs. ACL patients with non-contact sports, G allele vs. T allele. P-value <0.05 indicates statistical significance. ACL, anterior cruciate ligament; OR, odds ratio; CI, confidence interval; NS, not significant.