Table 4.
Multivariate analysis of OS in low- and high-risk patients after PCT using step-wise method
| Low-risk patients | High-risk patients | |||||
|---|---|---|---|---|---|---|
| Characteristic | HR | 95% CI | P-value | HR | 95% CI | P-value |
| Age (years) | NS | 1.27 | 0.96–1.68 | 0.089 | ||
| N stage | 1.85 | 0.99–3.45 | 0.055 | 1.38 | 0.97–1.96 | 0.074 |
| Metastatic site | ||||||
| Lung vs. Bone | NS | 0.83 | 0.48–1.42 | 0.493 | ||
| Liver vs. Bone | NS | 1.03 | 0.65–1.62 | 0.911 | ||
| Distant nodal vs. Bone | NS | 0.90 | 0.43–1.87 | 0.774 | ||
| Multiple vs. Bone | NS | 2.94 | 2.10–4.11 | < 0.001 | ||
| LRRT | 0.35 | 0.21–0.58 | < 0.001 | NS | ||
Abbreviations: NS non-significant, HR hazard ratio, CI confidence interval, LRRT locoregional radiotherapy
All potential prognostic factors were involved in the analysis. Two factors remained in low-risk patients and three factors remained in high-risk patients
HRs were calculated for Age (years) (>47 vs. ≤47); N stage (N2–3 vs. N0–1); LRRT (Yes vs. No)