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. 2019 Jan 21;17:35. doi: 10.1186/s12967-019-1777-7

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — GSEA analysis of MADNT expression data. a Prominent transcriptional patterns in NPs. The diagram showed GSEA plots for 5 pathways recapitulating the main difference between NPs and PPs (NPs were shown at left-hand side in GSEA plot, PPs right-hand side). The vertical axis in the upper graph indicates Enrichment Score (ES) for genes in each gene set. The barcode plot indicates the position of genes in each gene set. Red and blue colors represent positive and negative Pearson correlation with HIV progression. b Functional annotation of up regulated genes with FDR less than 0.05 in the validating set (GSE87620)