Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jan 21;7:16. doi: 10.1186/s40425-018-0464-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 4 — The T-PNU anti-tumor response consists of infiltrating and activated T cells. a, Gene set enrichment analysis of gene sets involved in T cell activation. Depicted is T-PNU vs. untreated. FDR: false discovery rate. b, Network cluster of gene sets with overlapping genes with TCR pathway function. The network includes 22 gene sets and 5448 genes (see Additional file 1: Table S1). c-e, Heatmaps of selected BIOCARTA THELPER, IL12 and TH1TH2 pathway gene sets, respectively (see Additional file 1: Figure S5 and S6 for more gene set heatmaps). f, MiXCR TCRβ CDR3 clonotype analysis. TCRβ CDR3 diversity (unique clones) plotted against TCRβ CDR3 abundance (read count). Donut plots depict clonotype distribution for one selected sample per cohort