Table 3.

A summary of the diagnostic power of miRNAs, conventional biomarkers, and the combination of the new and conventional markers. AUC = Area under the ROC curve. CI = Confidence Interval

	AUC	95%CI	Pvalue	sensitivity%	Specificity%
CA125	0.905	0.834 - 977	<0.0001	79.41%	93.33%
HE4	0.820	0.716 - 0.923	<0.0001	77.50%	86.21%
Mir-1307	0.671	0.550 - 0.791	0.0054	33.33%	94.29%
Mir-375	0.788	0.665 - 0.890	<0.0001	61.76%	87.88%
Mir-1307+Mir-375	0.837	0.725 - 0.917	<0.0001
HE4+CA125	0.937	0.857 - 0.983	<0.0001
Mir-1307+CA125	0.959	0.873 - 0.981	<0.0001
Mir-1307+HE4	0.857	0.730 - 0.919	<0.0001
Mir-1307+CA125+HE4	0.970	0.892 - 0.997	<0.0001
Mir-375+CA125	0.940	0.870 - 0.989	<0.0001
Mir-375+HE4	0.857	0.792 - 0.960	0.0012
Mir-375+CA125+HE4	0.945	0.904 - 0.999	<0.0001