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. 2019 Jan 22;19:79. doi: 10.1186/s12879-018-3659-7

Table 3.

Detailed numbers of cases showing each type of neurological complication associated with different serotype of virus of severe HFMD (N = 3510) a

CNSb complications EV-A71 CV-A16 Other EVs Total x2 p
aseptic meningitis(Survivors) 1088(31.40) 95(2.71) 131(3.73) 1314(37.44) 54.47 0.000
encephalitis(Survivors) 1604(45.70) 125(3.56) 363(10.34) 2092(59.60)
Encephalomyelitis(Survivors) 33(0.94) 3(0.09) 4(0.11) 40(1.14)
Pulmonary oedema/ haemorrhage 10(0.28) 0(0.00) 1(0.03) 11(0.31)
Acute flaccid paralysis(Survivors) 2(0.06) 0(0.00) 1(0.03) 3(0.09)
Brainstem encephalitis(Survivors) 3(0.09) 1(0.03) 0(0.00) 3(0.09)
Cardiorespiratory failure(Survivors) 4(0.11) 2(0.06) 0(0.00) 6(0.17)
Death 39(1.11) 0(0.00) 2(0.06) 41(1.17)
Total 2783(79.29) 225(6.41) 502(14.30) 3510(100.00)

aData outside the parentheses are the number of severe HFMD cases, data in parentheses are % (n/N)

bCNS: Central nervous system