Table 1.

Size distribution and zeta potential of nanoparticles

	Particle size (nm)	Zeta potential (mV)	PDI
Blank NPs	74.87 ± 0.19	21.26 ± 0.73	0.225 ± 0.003
MP-NPs	107.76 ± 1.68*	20.53 ± 1.34	0.251 ± 0.001
NEP1-40-MP-NPs	192.19 ± 4.43#	− 8.04 ± 3.99	0.263 ± 0.002

Results are expressed as mean ± SD from three independent experiments

MP methylprednisolone, NP nanoparticle, PDI polydispersity index

* P < 0.0001 vs. MP-NPs and ^# P < 0.0001 vs. NEP_1-40-MP-NPs