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. 2019 Jan 21;38:27. doi: 10.1186/s13046-019-1025-2

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Expression of Gab1 is upregulated in metastatic BCa tissues. a Analysis of datasets from Oncomine database shows that Gab1 expression is upregulated in BCa tissues when compared to the normal mammary tissues. b Expression of Gab1 is significantly upregulated in BCa tissues with lymph node metastasis when compared to that with primary tumor only. c Expression of Gab1 is measured by IHC staining in tumor tissues from a luminal, HER2 or TNBC subtype BCa patient and in mammary tissue from a benign mammary hyperplastic control respectively. d Expression of Gab1 is measured by IHC staining in tumor tissues with or without metastasis from HER2 or TNBC subtype BCa patients. Scale Bar: 100 μm, P: patient, Data are presented as means ± SEM. *: p < 0.05, **: p < 0.01