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. 2019 Jan 21;19:96. doi: 10.1186/s12885-019-5290-4

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — TNBCs exhibited higher mRNA expression of CCNE1 and TPX2 compared with non-TNBCs (Wilcoxon signed rank test) in (a) METABRIC: TNBC (n = 299) and non-TNBC (n = 1605) (p < 0.0001 for both CCNE1 and TPX2) and in (b) TCGA: TNBC (n = 115) and non-TNBC (n = 976) (p < 0.0001 for both CCNE1 and TPX2), y-axis is the log2 of TPM values by RSEM. In TNBCs, CCNE1 is significantly co-overexpressed with TPX2 in (c) METABRIC: TNBC (n = 299, p < 0.001, r = 0.65) and in (d) TCGA: TNBC (n = 115, p < 0.001, r = 0.63)