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. 2019 Jan 22;16:3. doi: 10.1186/s12014-019-9223-7

Table 2.

Correlations of protein expression levels with clinicopathological features

Clinico-path parameters No of cases (%) HLAB 14-3-3 β LTBP-3 ADAMTS2 Wnt-5a MRLC 2/3 Jagged-2 nm23 H2 SRPX RECK
Age 0.923 0.273 0.132 0.246 0.437 0.173 0.644 0.745 0.145 0.559
 < 65 35 (29)
 ≥ 65 84 (71)
Gender 0.556 0.363 0.178 0.938 0.562 0.709 0.515 0.866 0.681 0.215
 F 59 (50)
 M 60 (50)
Tumor location 0.230 0.318 0.231 0.444 0.317 0.078 0.589 0.736 0.534 0.036
 Colon 82 (69)
 Rectum 37 (31)
Histological type 0.106 0.001* 0.952 0.621 0.192 0.792 0.044* 0.158 0.526 0.659
 Non mucinous 102 (86)
 Mucinuo 16 (14)
Histological grade 0.020* 0.031* 0.743 0.326 0.266 0.402 0.646 0.032* 0.149 0.327
 High grade 95 (81)
 Low grade 23 (191)
Vascular invasion 0.556 0.200 0.500 0.730 0.279 0.584 0.038* 0.048* 0.401 0.166
 Negative 90 (76)
 Positive 29 (24)
Perineural invasion 0.017* 0.466 0.194 0.457 0.300 0.598 0.664 0.080 0.925 0.747
 Negative 109 (92)
 Positive 9 (8)
TNM stages 0.394 0.226 0.647 0.664 0.508 0.403 0.374 0.147 0.184 0.257
 I 20 (17)
 II 42 (36)
 III 34 (29)
 IV 21 (18)
Distant metastasis 0.307 0.850 0.003* 0.013* 0.503 0.833 0.808 0.418 0.681 0.210
 No 89 (75)
 Yes 29 (25)
Nodal status 0.227 0.417 0.403 0.336 0.894 0.101 0.283 0.413 0.463 0.194
 Negative 66 (58)
 Positive 47 (42)
Depth of invasion 0.426 0.041* 0.497 0.855 0.095 0.152 0.054 0.092 0.110 0.245
 T1/T2 23 (20)
 T3/T4 93 (80)
5-year recurrence# 0.104 0.120 0.075 0.041* 0.671 0.781 0.763 0.761 0.673 0.654
 Recurrence free 58 (79)
 Recurrence 15 (21)
Cause of death 0.025* 0.139 0.005* 0.055 0.380 0.650 0.488 0.144 0.390 0.265
 CRC 37 (30)
 Other cause 87 (70)

*p < 0.05 is considered significant

# Presence of absence of local or distant metachronous recurrence within 5 year follow-up