Table III.
Summary of surgical outcome in the consolidation group compared with the control group.
| Parameter | Consolidation group, no. (%) | Control group, no. (%) | P-value |
|---|---|---|---|
| No. of patients | 76 | 80 | − |
| pCR + near pCRa | 25 (32.80) | 13 (16.25) | 0.015 |
| Anal preservation | 56 (73.60) | 53 (66.20) | 0.312 |
| Resection with negative margins | 73 (96.10) | 72 (90.00) | 0.140 |
| T downstaging (ypT<cT) | 50 (65.8) | 39 (48.6) | 0.032 |
| N downstaging (ypN<cN) | 42 (55.30) | 28 (35.00) | 0.011 |
a
Near pCR rate being defined by the finding of only isolated residual tumor cells or small groups of residual cancer cells in the rectal wall with no tumor cells in the lymph nodes. pCR, pathologic complete response; T downstaging, tumor downstaging; N downstaging, node downstaging.