Table IV.
Proportions of high and low TIL numbers in EarR, LateR, and NoR cases, in association with clinicopathological factors.
| Number of TILs (%) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| EarR | LateR | NoR | |||||||
| Variable | High | Low | P-value | High | Low | P-value | High | Low | P-value |
| TILs | |||||||||
| ≤50 | 12 (54.5) | 70 (43.2) | 0.317 | 3 (17.6) | 46 (39.3) | 0.068 | 16 (37.2) | 104 (37.4) | 0.979 |
| >50 | 10 (45.4) | 92 (56.7) | 14 (82.3) | 71 (60.6) | 27 (62.7) | 174 (62.5) | |||
| Tumor size (mm) | |||||||||
| ≤20 | 6 (27.2) | 43 (26.5) | 0.942 | 4 (23.5) | 40 (34.1) | 0.369 | 24 (55.8) | 163 (58.6) | 0.727 |
| >20 | 16 (72.7) | 119 (73.4) | 13 (76.4) | 77 (65.8) | 19 (44.1) | 115 (41.3) | |||
| Lymph node metastases | |||||||||
| Negative | 11 (50.0) | 82 (50.6) | 0.956 | 5 (29.4) | 74 (63.2) | 0.008b | 29 (67.4) | 238 (85.6) | 0.004 |
| Positive | 11 (50.0) | 80 (49.3) | 12 (70.5) | 43 (36.7) | 14 (32.5) | 40 (14.3) | |||
| Estrogen receptor (%) | |||||||||
| <10 | 1 (4.5) | 15 (9.2) | 0.622 | 1 (5.8) | 9 (7.6) | 0.917 | 8 (18.60) | 19 (6.8) | 0.045a |
| 10–50 | 6 (27.2) | 51 (31.4) | 5 (29.4) | 38 (32.4) | 12 (27.91) | 70 (25.1) | |||
| ≥50 | 15 (68.1) | 96 (59.2) | 11 (64.7) | 70 (59.8) | 23 (53.49) | 189 (67.9) | |||
| Progesterone receptor (%) | |||||||||
| ≤20% | 9 (40.9) | 76 (46.9) | 0.594 | 9 (52.9) | 50 (42.7) | 0.430 | 27 (62.7) | 106 (38.1) | 0.002b |
| >20% | 13 (59.0) | 86 (53.0) | 8 (47.0) | 67 (57.2) | 16 (37.2) | 172 (61.8) | |||
| Histological grade | |||||||||
| 1 or 2 | 13 (59.0) | 118 (72.8) | 0.194 | 9 (52.9) | 97 (82.9) | 0.008b | 32 (74.4) | 246 (88.4) | 0.020a |
| 3 | 9 (40.9) | 44 (27.1) | 8 (47.0) | 20 (17.0) | 11 (25.5) | 32 (11.5) | |||
| Ki 67 (%) | |||||||||
| ≤20 | 10 (45.4) | 126 (77.7) | 0.002b | 11 (64.7) | 103 (88.0) | 0.023a | 28 (65.1) | 237 (85.2) | 0.002b |
| >20 | 12 (54.5) | 36 (22.2) | 6 (35.2) | 14 (11.9) | 15 (34.8) | 41 (14.7) | |||
a
P<0.05
b
P<0.01. EarR, early recurrence; LateR, late recurrence; NoR, no recurrence; Ki67, Ki67 Labeling index; TILs, tumor infiltrating lymphocytes.