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. 2018 Dec 4;17(2):1646–1654. doi: 10.3892/ol.2018.9793

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 6. — Increased IGF1R levels are inversely correlated with Let-7b in OS tissues. (A) The mRNA expression of IGF1R in the OS tissues and their matched adjacent non-tumor tissues was assessed using RT-qPCR analysis. (B) IGF1R mRNA level was inversely correlated with Let-7b in osteosarcoma T1-T2 stage using Spearman's correlation analysis. (C) The mRNA expression of IGF in the OS tissues and their matched adjacent non-tumor tissues was assessed using RT-qPCR analysis. (D) The IGF mRNA level was positively correlated with IGF1R in OS T1-T2 stage using Spearman's correlation analysis. *P<0.05 vs. Non tumor tissues. IGF1R, insulin-like growth factor 1 receptor; IGF, insulin-like growth factor; RT-qPCR, reverse transcription-quantitative polymerase chain reaction; OS, osteosarcoma; T stage, Tumor stage.