Table II.

Top ten differentially expressed mRNAs for each comparison.

Gene symbol	P-value	Fold-change	Regulation
C vs. N
DPP10	7.85×10−6	3,029.7207	Upregulated
CSRP1	2.43×10−5	1,280.9022	Downregulated
TPM1	1.21×10−4	465.1485	Downregulated
PALLD	9.82×10−5	463.9496	Downregulated
KIT	1.04×10−5	454.6385	Upregulated
PLAT	5.23×10−5	415.0655	Upregulated
ANO1	9.09×10−6	397.9115	Upregulated
SLMAP	1.18×10−5	372.9152	Downregulated
MYL9	6.12×10−5	258.0424	Downregulated
RGS5	3.75×10−4	226.5819	Downregulated
C vs. Y
OGN	3.51×10−4	731.1902	Upregulated
CLPTM1L	3.42×10−4	157.8434	Upregulated
LDHA	2.51×10−3	83.7515	Upregulated
TM4SF1	9.60×10−4	69.0364	Upregulated
BHLHE40	3.76×10−5	67.7466	Upregulated
MT1X	2.60×10−3	52.4122	Upregulated
MT2A	2.42×10−3	49.3582	Upregulated
C7	5.81×10−3	45.7806	Upregulated
SPP1	3.40×10−3	39.3369	Upregulated
TMEM45A	2.78×10−4	38.8151	Upregulated
Y vs. N
DPP10	9.41×10−6	2,421.0703	Upregulated
CNN1	3.59×10−4	1,231.3666	Downregulated
MYH11	1.04×10−3	1,125.5151	Downregulated
TPM1	2.88×10−4	589.9242	Downregulated
PALLD	5.93×10−6	583.9103	Downregulated
PLAT	7.13×10−5	558.9153	Upregulated
ANO1	2.64×10−6	457.2661	Upregulated
F2RL2	3.66×10−4	436.2676	Upregulated
KIT	8.03×10−6	372.8208	Upregulated
SORBS1	5.04×10−4	354.0606	Downregulated

N, normal gastric tissue samples; Y, primary gastrointestinal stromal tumor samples; C, imatinib mesylate-resistant gastrointestinal stromal tumor samples.