Table 1. Markers of recent hepatitis C infectiona according to survey year, demographics and risk factor variables, among people who inject drugs, England, Wales and Northern Ireland, 2011–13 (n = 2,816).
Variable | Category | N | Combined markers of recent infection | RNA marker of recent infection | Avidity marker of recent infection | |||
---|---|---|---|---|---|---|---|---|
Positive | % | Positive | % | Positive | % | |||
Year | 2011 | 791 | 33 | 4.2 | 15 | 1.9 | 18 | 2.3 |
2012 | 969 | 58 | 6.0 | 18 | 1.9 | 40 | 4.1 | |
2013 | 1,056 | 56 | 5.3 | 24 | 2.3 | 32 | 3.0 | |
Age | <30 | 957 | 56 | 5.9 | 29 | 3.0 | 27 | 2.8 |
30–39 | 1,277 | 62 | 4.9 | 19 | 1.5 | 43 | 3.4 | |
≥40 | 582 | 29 | 5.0 | 9 | 1.5 | 20 | 3.4 | |
Gender | Male | 2,099 | 101 | 4.8 | 38 | 1.8 | 63 | 3.0 |
Female | 717 | 46 | 6.4 | 19 | 2.6 | 27 | 3.8 | |
Regional prevalence | Low (<40%) | 1,114 | 50 | 4.5 | 26 | 2.3 | 24 | 2.2 |
Medium (40–55%) | 768 | 35 | 4.6 | 11 | 1.4 | 24 | 3.1 | |
High (>55%) | 934 | 62 | 6.6 | 20 | 2.1 | 42 | 4.5 | |
Injecting duration | <1 year | 157 | 9 | 5.7 | 3 | 1.9 | 6 | 3.8 |
1–5 years | 783 | 39 | 5.0 | 24 | 3.1 | 15 | 1.9 | |
6–10 years | 591 | 36 | 6.1 | 12 | 2.0 | 24 | 4.1 | |
11–14 years | 499 | 22 | 4.4 | 7 | 1.4 | 15 | 3.0 | |
15–19 years | 457 | 20 | 4.4 | 7 | 1.5 | 13 | 2.8 | |
≥20 years | 329 | 21 | 6.4 | 4 | 1.2 | 17 | 5.2 | |
Homelessness | Never | 696 | 23 | 3.3 | 11 | 1.6 | 12 | 1.7 |
Yes, not past year | 1,063 | 58 | 5.4 | 24 | 2.3 | 34 | 3.2 | |
Yes, past year | 1,007 | 65 | 6.5 | 22 | 2.2 | 43 | 4.3 | |
Imprisonment | Never | 1,129 | 54 | 4.8 | 22 | 1.9 | 32 | 2.8 |
1–4 times | 886 | 33 | 3.7 | 14 | 1.6 | 19 | 2.1 | |
≥5 times | 801 | 60 | 7.5 | 21 | 2.6 | 39 | 4.9 | |
Crack injecting | No | 2,268 | 87 | 3.8 | 37 | 1.6 | 50 | 2.2 |
Yes | 548 | 60 | 10.9 | 20 | 3.6 | 40 | 7.3 | |
Speed (amphetamine) injecting | No | 2,335 | 127 | 5.4 | 49 | 2.1 | 78 | 3.3 |
Yes | 481 | 20 | 4.2 | 8 | 1.7 | 12 | 2.5 | |
NSP use | Never/not in past year | 499 | 25 | 5.0 | 9 | 1.8 | 16 | 3.2 |
In past year | 2,300 | 121 | 5.3 | 48 | 2.1 | 73 | 3.2 | |
Injecting and sharing past month | Did not inject past month | 674 | 18 | 2.7 | 10 | 1.5 | 8 | 1.2 |
Injected and did not share | 1,418 | 59 | 4.2 | 21 | 1.5 | 38 | 2.7 | |
Injected and shared | 724 | 70 | 9.7 | 26 | 3.6 | 44 | 6.1 |
NSP: needle and syringe programmes.
a Antibody-negative with RNA and weak avidity of antibody.