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. 2018 Nov 15;17(21-22):2460–2473. doi: 10.1080/15384101.2018.1542897

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Figure 5. — The effect of EZH2 overexpression on cell migration. (a) Left panel, The cell migratory activity was analyzed by wound healing assay with EZH2 cDNA transfection and rottlerin treatment. Control: pcDNA3.0 cDNA: EZH2 cDNA; Both: EZH2 cDNA+ rottlerin. Right panel, Quantitative results are illustrated for left panel. *P < 0.05, compared with control; ^#P < 0.05 compared with rottlerin treatment alone or EZH2 cDNA transfection alone. (b) The expression of EZH2 was performed by western blotting in prostate cancer cells with EZH2 cDNA transfection and rottlerin treatment. (c) Quantitative results are illustrated for top panel. *P < 0.05, compared with control; #P < 0.05, compared with rottlerin treatment alone or EZH2 cDNA transfection alone.