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. 2018 Nov 15;17(21-22):2460–2473. doi: 10.1080/15384101.2018.1542897

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Figure 6. — The effect of EZH2 downregulation on cell growth, apoptosis and invasion (a) CellTiter-Glo luminescence assay was applied for detecting the effect of EZH2 siRNA in combination with rottlerin treatment on prostate cancer cell growth. **P < 0.01, compared with control; ^#P < 0.05 compared with rottlerin treatment or EZH2 siRNA transfection. Control: siRNA control; SiRNA: EZH2 siRNA; Both: rottlerin + EZH2 siRNA. (b) Flow cytometry was used to describe in PC3 and DU145 cells. (c) Left panel, Invasion assay was exerted in prostate cancer cells after EZH2 siRNA transfection and rottlerin treatment. Right panel, quantitative results are illustrated for left panel. **P < 0.01, vs control; ^#P < 0.05 vs rottlerin treatment or EZH2 siRNA transfection.