Skip to main content
. Author manuscript; available in PMC: 2019 Jan 22.
Published in final edited form as: Cancer Discov. 2018 Jan 4;8(3):288–303. doi: 10.1158/2159-8290.CD-16-1406

Figure 3.

Figure 3.

(A) Graph of droplet digital PCR signal for AR-V7 (no pre-amplification) and TMPRSS2:ERG (after specific targeted amplification; see Methods) for varying numbers of 22Rv1 cells and VCaP cells, respectively, micromanipulated into healthy donor whole blood and processed using the CTC-iChip. (B) Tables showing number of metastatic prostate cancer patients and healthy donors with AR-V7 droplet digital PCR signal and/or TMPRSS2:ERG ddPCR signal.(C) Concordance of AR-V7 and TMPRSS2:ERG status in prostate CTCs and matched archival FFPE specimens of prostate cancer biopsy or prostatectomy tissues from prostate cancer patients, as measured by droplet digital PCR assays.