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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Genet Epidemiol. 2018 May 29;42(5):418–433. doi: 10.1002/gepi.22131

Figure 3: Type I error when J=50, InSIDE condition violated, and there is directional pleiotropy.

Figure 3:

Each bar represents results over 5×104 simulations. Evaluated at α = 0.05. First panel represent when low LD (plots with A). Second panel represents when strong LD (plots with B). From left to right correspond to: correlation between θj and βE,j is 0.125, 0.5, or 0.9.