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. Author manuscript; available in PMC: 2019 Jan 22.
Published in final edited form as: J Invest Dermatol. 2017 Jun 7;137(10):2187–2196. doi: 10.1016/j.jid.2016.12.033

Figure 3. Long-term growth of dual resistant melanoma is greatly inhibited by triple therapy with BI-D1870 and BRD7389.

Figure 3.

2D colony formation assays were performed with initial seeding of 5,000 cells per well. Cells were allowed to settle for 48 hours before being treated with 5 μM BI-D1870 or 5 μM BRD7389 ± 5 μM vemurafenib and 150 nM selumetinib for 14 days.Media and drug were replaced every 72 hours after commencement of drug treatment, N = 3.