Table 2.
CYP1A2 induction status and genotype for 24 healthy volunteers
| Induction Status | Genotype | SNPa | Sex (n) | Race (n) | |
|---|---|---|---|---|---|
| −3860G>A | −163C>A | ||||
| N | *1A/*1A | GG | CC | M (1), F (3) | White (3), Asian (1) |
| N | *1C/*1F | GA | CA | M (1), F (1) | Asian (1), PI (1) |
| N | *1C*1F/*1C*1F | AA | AA | M (2), F (1) | Asian (2), PI (1) |
| H | *1A/*1F | GG | CA | M (6), F (5) | White (9), Asian (2) |
| H | *1F/*1F | GG | AA | M (2), F (2) | White (4) |
F, female; H, hyperinducer; M, male; N, normal metabolizer; SNP, single‐nucleotide polymorphism; PI, Pacific Islander.
aAll subjects harbored the T allele for −739T>G (rs2069526) and the C allele for −729C>T (rs12720461).