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. 2019 Jan 23;364:k5420. doi: 10.1136/bmj.k5420

Table 5.

Association of individual fried food consumption with cancer mortality among 106 966 postmenopausal women. Data are hazard ratios (95% confidence intervals) unless indicated otherwise

Fried food items Frequency of consumption P for trend
None <2 servings/month 2-3 servings/month ≥1 serving/week
Fried chicken:
 No of deaths/participants 5345/68 709 1721/21 980 794/10 268 498/6009
 Age adjusted model 1.00 (ref) 1.06 (1.01 to 1.12) 1.08 (1.01 to 1.17) 1.20 (1.10 to 1.32) <0.001
 Multivariable model 1 1.00 (ref) 1.02 (0.96 to 1.08) 0.98 (0.91 to 1.07) 1.03 (0.93 to 1.14) 0.84
 Multivariable model 2 1.00 (ref) 1.01 (0.95 to 1.07) 0.98 (0.90 to 1.06) 1.03 (0.93 to 1.14) 0.99
Fried fish/shellfish:
 No of deaths/participants 4735/60 169 1837/24 958 1082/13 489 704/8350
 Age adjusted model 1.00 (ref) 0.95 (0.90 to 1.01) 1.07 (0.99 to 1.14) 1.13 (1.05 to 1.23) 0.004
 Multivariable model 1 1.00 (ref) 0.92 (0.87 to 0.97) 0.99 (0.92 to 1.06) 1.05 (0.97 to 1.15) 0.70
 Multivariable model 2 1.00 (ref) 0.92 (0.87 to 0.97) 0.99 (0.92 to 1.06) 1.05 (0.96 to 1.14) 0.80
Other fried foods:
 No of deaths/participants 1588/20 484 1859/22 699 1528/19 468 3373/44 315
 Age adjusted model 1.00 (ref) 1.10 (1.03 to 1.18) 1.09 (1.02 to 1.17) 1.13 (1.06 to 1.20) <0.001
 Multivariable model 1 1.00 (ref) 1.09 (1.02 to 1.17) 1.05 (0.98 to 1.13) 1.04 (0.97 to 1.11) 0.94
 Multivariable model 2 1.00 (ref) 1.09 (1.02 to 1.17) 1.05 (0.98 to 1.13) 1.03 (0.97 to 1.11) 0.95

Multivariable model 1=age at baseline, race/ethnicity, education, annual income, whether they were from the observational study or the clinical trial, unopposed estrogen use, estrogen+progesterone use, smoking status, physical activity, coffee intake, total energy intake, diet quality score, baseline diabetes status, baseline cardiovascular status, and baseline cancer status; multivariable model 2=multivariable model 1+body mass index; ref=reference.