Compound II, II-3, and III were tested for selective inhibition of RGS17 over RGS7, RGS10, and RGS18. For all three compounds, RGS17 was the most potently inhibited, with a statistically significant reduction in signal compared to the inhibition observed for RGS7, RGS10, and RGS18. Significance determined via one way ANOVA with Holm-Sidak multiple comparison post hoc analysis. Significance shown on graph are the multiple comparison analysis with respect to RGS17, *** - P < 0.001. Data are n=3 in duplicate ± SD.