Table 2. Top-ranked compounds using multiple levels of biological action.

The names of the drugs previously shown to extend lifespan in animal models are in bold. The numeric values represent the ranking of the drugs when different sources of data (columns) are used. The last column is the ranking average (Avg.) for each drug in the 7 ranked lists.

Drug name	Status	Genes	PPI	Gene ontology			Pathways		Avg.
				BP	CC	MF	KEGG	Reactome
Tanespimycin	Investigational	5	26	57	43	44	39	9	31.86
Imatinib	Approved	63	3	21	34	12	66	38	33.86
Sunitinib	Approved	2	1	59	31	31	56	63	34.71
Trichostatin	Experimental	83	41	19	54	13	41	52	43.29
Geldanamycin	Investigational	32	37	87	76	47	13	21	44.71
Sorafenib	Approved	16	68	11	15	8	155	42	45.00
Dasatinib	Approved	41	12	43	81	62	49	35	46.14
Erlotinib	Approved	27	6	93	85	71	64	7	50.43
Etoposide	Approved	23	11	20	90	32	120	67	51.86
Celecoxib	Approved	10	2	33	42	34	180	70	53.00