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. 2019 Jan 15;50(1):37–50. doi: 10.1016/j.immuni.2018.12.027

Figure 2.

Figure 2

The Proposed Spectrum of Dendritic Cell Subsets

Shown on this hypothetical scheme are canonical pDCs and cDCs (including cDC1 and cDC2) and the intermediate “non-canonical” populations including non-canonical pDCs (nc-pDC) and cDCs (nc-cDC). Shown are functional properties including the IFN-I production capacity and antigen presentation capacity in the steady state, expression of key transcription factors, and surface markers in the human (Alcántara-Hernández et al., 2017, Villani et al., 2017) and mouse (Bar-On et al., 2010, Lau et al., 2016, Dekker et al., 2018). Italicized genes and markers denote expression based on reported transcript levels.