Figure 3.
Substitution for the discriminative stimulus effects of Δ9-tetrahydrocannabinol: Top panels show percentage of total responses made on the drug-appropriate lever. Bottom panels show rate of responding in responses per second (r/s). All of the cathinones fully substituted for the discriminative stimulus effects of Δ9-tetrahydrocannabinol (≥80% drug-appropriate responding). n=6 unless otherwise shown. Ctrl indicates vehicle and Δ9-THC control values. * indicates response rate different from vehicle control (p < 0.05).