Table 2. Comparisons between Treatment-Response and Non-Response Groups.

	Response Group (n = 47)	Non-Response Group (n = 179)	P
Demographics
Age (years)	64.3 ± 7.1	65.2 ± 7.5	0.509*
Male:female	45:2	167:12	0.375†
BMI (kg/m2)	24.37 ± 3.37	23.49 ± 3.09	0.092*
PY	50.04 ± 28.03	43.62 ± 29.27	0.186*
GOLD stage (n)			0.855†
I	5	20
II	26	95
III	14	52
IV	2	12
Initial PFT
FEV1 (%)	61.6 ± 16.7	65.6 ± 19.1	0.200*
FVC (%)	91.4 ± 16.8	92.8 ± 19.0	0.632*
FEV1/FVC	48.9 ± 11.5	50.5 ± 11.8	0.393*
FEF25–75 (%)	23.6 ± 12.2	28.7 ± 16.5	0.487*
TLC (%)	110.3 ± 23.0	107.1 ± 23.8	0.425*
VC (%)	89.4 ± 17.0	93.8 ± 23.3	0.229*
RV (%)	134.5 ± 58.3	120.8 ± 63.3	0.194*
DLCO (%)	83.9 ± 21.8	82.9 ± 22.8	0.789*
6MWD (m)	455.8 ± 83.4	439.3 ± 75.5	0.209*
CT indices
EI	12.1 ± 9.9	15.7 ± 12.4	0.066*
ATI_-856	40.0 ± 19.5	40.8 ± 20.3	0.801*
ATI_subtraction_1	34.5 ± 31.0	28.3 ± 14.6	0.048*
ATI_subtraction_2	59.1 ± 26.0	56.8 ± 26.4	0.599*
ATI_emphysema	8.3 ± 8.6	11.4 ± 11.6	0.042*
ATI_hyperinflated	20.3 ± 10.2	19.6 ± 10.6	0.693*
ATI_normal	27.7 ± 16.8	24.6 ± 17.2	0.267*
Pi10-FWHM (mm)	4.6 ± 0.4	4.5 ± 0.4	0.051*
Pi10-IBHB (mm)	4.6 ± 0.8	4.2 ± 0.8	0.002*

Unless otherwise noted, data are means ± SD. ^*Independent-sample t test, ^†Chi-squared test. ATI = air-trapping index, DL_CO = diffusing capacity of lung for carbon monoxide, EI = emphysema index, FEF₂₅₋₇₅ = forced expiratory flow between 25% and 75% of FVC, FEV₁ = forced expiratory volume in 1 second, FVC = forced vital capacity, FWHM = full-width-half-maximum, IBHB = integral-based half-band, PFT = pulmonary function test, Pi10 = square root of airway wall area of theoretical airway with internal perimeter of 10 mm, RV = residual volume, TLC = total lung capacity, VC = vital capacity, 6MWD = 6-minute walk distance