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Table 1. Demographic characteristics, standard cardiovascular risk factors, and laboratory findings in patients with or without carotid plaque.

Variables (N = 331) Without carotid plaque (N = 254) Carotid plaque (N = 77) p value
Age (years) 45 ± 8 51 ± 9 < 0.001
Gender (male)  68%   82%  0.027
BMI (kg/m2) 31 ± 4.7 30 ± 4.2 0.836
Waist circumference (cm) 100 ± 110 104 ± 13 0.038
Hypertension %  61%   75%  0.019
Diabetes mellitus %  7%   12%  0.124
Smoking status %  42%   60%  0.026
Hyperlipidemia %  34%   45%  0.053
Family history of CAD %  41%   56%  0.066
Glucose (mg/dL) 102 ± 28 111 ± 46 0.032
Creatinine (mg/dL) 0.83 ± 0.16 0.85 ± 0.13 0.258
Uric acid (mg/dL) 5.2 ± 1.4 5.9 ± 1.5 < 0.001
Total cholesterol (mg/dL) 213 ± 40 228 ± 42 0.003
LDL-cholesterol (mg/dL) 134 ± 34 146 ± 39 0.009
HDL-cholesterol (mg/dL) 45 ± 12 44 ± 13 0.370
Triglycerides (mg/dL) 171 ± 109 201 ± 158 0.049
CRP (mg/dL) 0.48 ± 0.52 0.54 ± 0.56 0.387
Epicardial adipose tissue thickness (mm) 5.4 ± 2.3 7.7 ± 2.6 < 0.001
CIMT (mean, mm) 0.78 ± 0.15 0.98 ± 0.12 < 0.001
Framingham risk score 6.6 ± 6.5 12.6 ± 9.3 < 0.001
Metabolic syndrome score 2.4 ± 1.6 3.0 ± 1.6 0.022

BMI, body mass index; CAD, coronary artery disease; CIMT, carotid intima-media thickness; CRP, C-reactive protein; HDL, high density lipoprotein; LDL, low density lipoprotein; SD, standard deviation.