Fig. 1.

The effect of PTX on the arthritis severity score in CIA mice. a Mice were injected with PTX (1.5, 1.0, 0.5 mg/kg) or normal saline eight times from day 35 after the first immunization. The arthritis severity score was recorded. b On day 50, the arthritis scores of three intervention groups declined compared with the CIA group. Additionally, the arthritis severity scores in the three PTX treatment groups and the CIA group were higher than that in the normal control group. #p < 0.05, ##p < 0.01 compared with CIA