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Effect of PTX on the expression of VEGF and HIF-1α in peripheral serum. The levels of VEGF (a) and HIF-1α (b) in serum were measured by ELISA. Values are expressed as the mean ± SEM. *p < 0.05, **p < 0.01 compared with the normal control group, #p < 0.05, ##p < 0.01 compared with the CIA group
