Table 10.
Outcomes of FRI treatment
| Proportional variable | Studies (N) | FRI (N) | Chi2 (p value) | I2 value (95% CI) | Pooled proportion (95% CI) |
|---|---|---|---|---|---|
| Primary healing | 93 | 3711 | * | 81% (77–84) | 85% (82–88) |
| Total healing | 92 | 3695 | * | 77% (72–81) | 93% (91–94) |
| Infection recurrence | 89 | 3598 | * | 73% (66–78) | 9% (7–11) |
| Amputation rate | 83 | 3226 | * | 50% (35–61) | 3% (3–5) |
| Continuous variable | Studies (N) | Patients (N) | Weighted meanb |
|---|---|---|---|
| Union time (months) | 47 | 1809 | 6.63 |
| Surgical revisionsa | 58 | 2110 | 0.31 |
| Complicationsa | 84 | 3436 | 0.38 |
| HLOS (months) | 14 | 415 | 1.39 |
*p < 0.0001
aPer patient
bSince most of the individual studies did not report a standard deviation (SD) or standard error, no pooled SD could be provided