Table 5.

Disease course and previous treatment

Disease course	n (%)	Mean ± SD
EDSS
Baseline	153 (100)	4.5 ± 2.2
12 months	152 (96.8)	4.5 ± 2.3
24 months	101 (64.3)	4.3 ± 2.2
36 months	77 (49.0)	4.1 ± 2.2
ARR in RRMS and SPMS PE ARR in RRMS and SPMS AE	98	1.55 ± 1.36 0.26 ± 0.52
ARR in NMO/NMOSD PE ARR in NMO/NMOSD AE	21	2.22 ± 1.89 0.42 ± 0.56
Time to first relapse (observed relapses; months)	20	5.35 ± 3.05

AE after enrollment [ARR after enrollment was over whole follow-up period (mean 2.19 ± 1.75 years)], ARR annualized relapse rate, EDSS Expanded Disability Status Scale, n number of available patient data, NMO neuromyelitis optica NMOSD neuromyelitis optica spectrum disease, PE prior to enrollment (ARR prior to enrollment was over 2 years), RRMS relapsing–remitting MS, SPMS secondary progressive MS, RRMS relapsing remitting data are expressed as mean ± SD where appropriate