Table 1.
Characteristics of Study Participants
| All Participants (N = 1,769) | Participants Without Adverse Plaque (n = 1,161) | Participants With Adverse Plaque (n = 608) | p Value | |
|---|---|---|---|---|
| Male | 997 (56) | 545 (47) | 452 (74) | <0.001 |
| Age, yrs | 57.6 ± 9.5 | 55.9 ± 9.8 | 60.8 ± 7.8 | <0.001 |
| Body mass index, kg/m2 | 29.6 ± 5.5 | 30.0 ± 5.8 | 28.8 ± 4.8 | <0.001 |
| Atrial fibrillation | 34 (1.9) | 20 (1.7) | 14 (2.3) | 0.399 |
| Smoking status | <0.001 | |||
| Current smoker | 330 (19) | 208 (18) | 122 (20) | |
| Ex-smoker | 593 (34) | 357 (31) | 236 (39) | |
| Nonsmoker | 845 (48) | 595 (51) | 250 (41) | |
| Hypertension | 608 (35) | 373 (32) | 235 (39) | 0.005 |
| Diabetes | 196 (11) | 128 (11) | 68 (11) | 0.919 |
| Family history of CHD | 765 (43) | 507 (44) | 258 (42) | 0.552 |
| Previous CHD | 178 (10) | 75 (6.5) | 103 (17) | <0.001 |
| Previous PAD | 31 (1.8) | 19 (1.6) | 12 (2) | 0.608 |
| Anginal symptoms | <0.001 | |||
| Typical angina | 654 (37) | 347 (30) | 307 (51) | |
| Atypical angina | 432 (24) | 293 (25) | 139 (23) | |
| Nonanginal | 683 (39) | 521 (45) | 162 (27) | |
| ASSIGN | 17.9 ± 11.0 | 16.1 ± 10.9 | 21.4 ± 10.6 | <0.001 |
| Coronary artery calcium score (Agatston units) | 21 [0–230] | 0 [0–34] | 281 [89–775] | <0.001 |
Values are n (%), mean ± SD, or median [interquartile range]. Values in bold indicate statistical significance.
ASSIGN = ASsessing cardiovascular risk using Scottish Intercollegiate Guidelines Network guidelines; CHD = coronary heart disease; PAD = peripheral arterial disease.