Table 4.

Univariable and Multivariable Analysis for Coronary Heart Disease Death or Nonfatal Myocardial Infarction Across the Total Population

	Univariable Analysis	p Value	Multivariable Analysis∗	p Value
Adverse plaque†	3.01 (1.61–5.63)	0.001	1.18 (0.55–2.52)	0.671
Coronary artery calcium score‡	1.23 (1.13–1.35)	<0.001	1.17 (1.04–1.33)	0.011
Obstructive coronary artery disease	3.35 (1.81–6.19)	<0.001	1.36 (0.63–2.93)	0.439
Cardiovascular risk score§	1.65 (1.13–2.41)	0.01	1.14 (0.74–1.75)	0.563

Values are hazard ratio (95% confidence interval). Values in bold indicate statistical significance.

^∗Log rank statistic 26.74 (p < 0.001), Harrell’s C-statistic 0.723 (standard error = 0.046).

^†Compared with patients without adverse plaque in the total population. Adverse plaque defined as the presence of positive remodeling or low-attenuation plaque.

^‡Per doubling of coronary artery calcium score.

^§ASSIGN score, per doubling of cardiovascular risk score.