Table 2.
Top probes in each PFC consensus signature. There are three columns shown for each signature, which denote the probe ID, gene symbols, and scores for the top 15 probes. (a) Consensus co-expression signatures, E1–E3. (b) Consensus co-methylation signatures, M1–M5
| (a) | ||||||||
|---|---|---|---|---|---|---|---|---|
| E1 | E2 | E3 | ||||||
| Probes | Genes | Scores | Probes | Genes | Scores | Probes | Genes | Scores |
| 209300_s_at | NECAP1 | 0.8463 | 202800_at | SLC1A3 | 0.8772 | 209769_s_at | SEPT5-GP1BB | 0.8030 |
| 212990_at | SYNJ1 | 0.8265 | 207761_s_at | METTL7A | 0.8247 | 217696_at | FUT7 | 0.7826 |
| 202854_at | HPRT1 | 0.8228 | 203908_at | SLC4A4 | 0.8194 | 214122_at | PDLIM7 | 0.7676 |
| 208841_s_at | G3BP2 | 0.8092 | 202936_s_at | SOX9 | 0.8180 | 216940_x_at | YBX1 | 0.7666 |
| 213745_at | ATRNL1 | 0.8031 | 201667_at | GJA1 | 0.8092 | 214105_at | SOCS3 | 0.7537 |
| 204552_at | INPP4A | 0.8022 | 212230_at | PPAP2B | 0.7954 | 209979_at | ADARB1 | 0.7524 |
| 201889_at | FAM3C | 0.8009 | 201876_at | PON2 | 0.7926 | 209730_at | SEMA3F | 0.7439 |
| 205352_at | SERPINI1 | 0.8005 | 212377_s_at | NOTCH2 | 0.7898 | 216680_s_at | EPHB4 | 0.7425 |
| 205280_at | GLRB | 0.7963 | 203296_s_at | ATP1A2 | 0.7888 | 207306_at | TCF15 | 0.7417 |
| 209274_s_at | ISCA1 | 0.7942 | 206465_at | ACSBG1 | 0.7684 | 216345_at | ZSWIM8 | 0.7385 |
| 211763_s_at | UBE2B | 0.7915 | 209210_s_at | FERMT2 | 0.7624 | 206824_at | CES1P1 | 0.7325 |
| 202670_at | MAP2K1 | 0.7909 | 221796_at | NTRK2 | 0.7613 | 216821_at | KRT8P11 | 0.7305 |
| 218042_at | COPS4 | 0.7866 | 212850_s_at | LRP4 | 0.7505 | 202828_s_at | MMP14 | 0.7244 |
| 221207_s_at | NBEA | 0.7864 | 205328_at | CLDN10 | 0.7432 | 216076_at | L3MBTL1 | 0.7219 |
| 213423_x_at | TUSC3 | 0.7861 | 203120_at | TP53BP2 | 0.7412 | 205212_s_at | ACAP1 | 0.7214 |
| (b) | ||||||||
|---|---|---|---|---|---|---|---|---|
| M1 | M2 | M3 | ||||||
| Probes | Genes | Scores | Probes | Genes | Scores | Probes | Genes | Scores |
| cg10717149 | SLC25A14 | 0.9911 | cg22655232 | PPP1R2P9 | 0.9784 | cg26765599 | NMRAL1 | 0.9040 |
| cg04317640 | SLC16A2 | 0.9910 | cg11049634 | BCOR | 0.9778 | cg06081917 | BFAR | 0.9013 |
| cg16221895 | EDA | 0.9908 | cg05130312 | LOC286467 | 0.9740 | cg17032990 | MAP4K4 | 0.8983 |
| cg14191108 | MAOA | 0.9907 | cg14372935 | PIR | 0.9722 | cg02473439 | CCAR1 | 0.8979 |
| cg10981178 | ZBTB33 | 0.9899 | cg06780606 | EDA | 0.9716 | cg02193425 | FAM50B | 0.8972 |
| cg26505478 | CUL4B | 0.9893 | cg09791535 | GPC4 | 0.9714 | cg02313013 | TMCC3 | 0.8942 |
| cg23696472 | TSPYL2 | 0.9892 | cg09192294 | LAS1L | 0.9701 | cg00489902 | POLE | 0.8926 |
| cg05806018 | AFF2 | 0.9890 | cg07801607 | ZMAT1 | 0.9696 | cg10521450 | SH3PXD2A | 0.8922 |
| cg11594566 | LINC00086 | 0.9884 | cg04690567 | PHF8 | 0.9683 | cg02041593 | SEMA5B | 0.8917 |
| cg10201390 | DYNLT3 | 0.9882 | cg00098732 | HS6ST2 | 0.9662 | cg00245075 | GALNT6 | 0.8911 |
| cg20749341 | LONRF3 | 0.9881 | cg12653510 | XIST | 0.9662 | cg19885979 | TRIM26 | 0.8902 |
| cg22164912 | GNL3L | 0.9877 | cg27551771 | KIAA1210 | 0.9639 | cg00452755 | RCC1 | 0.8900 |
| cg20766178 | NHSL2 | 0.9875 | cg01037726 | PNCK | 0.9627 | cg02450267 | MOG | 0.8876 |
| cg18989810 | DUSP9 | 0.9874 | cg04704683 | POF1B | 0.9617 | cg23384027 | NFE2 | 0.8875 |
| cg22604777 | MAGEH1 | 0.9874 | cg08209935 | ARMCX5 | 0.9602 | cg02713352 | B4GALNT1 | 0.8874 |
| M4 | M5 | |||||||
|---|---|---|---|---|---|---|---|---|
| Probes | Genes | Scores | Probes | Genes | Scores | |||
| cg12268888 | FAM198A | 0.8628 | cg12547839 | UBE2O | 0.8539 | |||
| cg09063372 | HDGF | 0.8506 | cg22330763 | SLC29A1 | 0.8421 | |||
| cg11150308 | SRP68 | 0.8505 | cg04101806 | AFF3 | 0.8203 | |||
| cg16129988 | UQCRC1 | 0.8468 | cg23400122 | MSRA | 0.8179 | |||
| cg11371394 | TGFBRAP1 | 0.8406 | cg26218110 | BAHCC1 | 0.8153 | |||
| cg04233747 | PRELID2 | 0.8403 | cg25119743 | CELF2 | 0.8023 | |||
| cg03330867 | TELO2 | 0.8398 | cg06372223 | SLC7A5 | 0.8023 | |||
| cg04426297 | B3GAT3 | 0.8394 | cg24897320 | CYB561D1 | 0.8008 | |||
| cg24695828 | ZNF566 | 0.8324 | cg14706739 | DMTN | 0.7987 | |||
| cg01923255 | ATG14 | 0.8321 | cg08202720 | PER2 | 0.7983 | |||
| cg26897054 | DEDD2 | 0.8317 | cg17518776 | PACSIN1 | 0.7970 | |||
| cg11111696 | ZNF438 | 0.8312 | cg20318252 | MSI2 | 0.7966 | |||
| cg25426560 | DHX16 | 0.8309 | cg24107728 | LRP8 | 0.7962 | |||
| cg05623562 | RBFA | 0.8300 | cg08506743 | NTM | 0.7943 | |||
| cg24715473 | CNEP1R1 | 0.8290 | cg20685981 | MEGF8 | 0.7929 | |||