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. 2019 Jan 22;9:315. doi: 10.1038/s41598-018-36668-7

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Changes of parameters over time. (A) Visual acuity change. (B) Sphere and spherical equivalent change. (C) Anterior keratometric change. (D) Posterior keratometric change. (E) Cylinder change. (F) Corneal thickness change. UDVA = Uncorrected distance visual acuity. CDVA = Corrected distance visual acuity. Anterior SimK = Mean anterior simulated keratometry. Anterior 3 mm K = Mean anterior keratometry in 3.0-mm zone. Posterior SimK = Mean posterior simulated keratometry. Anterior SimKcyl = Cylinder of anterior simulated keratometry. Anterior 3 mm Kcyl = Cylinder of anterior keratometry in 3.0-mm. Posterior SimKcyl = Cylinder of posterior simulated keratometry. TCT = Thinnest corneal thickness. CCT = Central corneal thickness. PCT = Peripheral corneal thickness. *Indicates statistical significance.