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. 2019 Jan 22;9:253. doi: 10.1038/s41598-018-36319-x

Table 1.

Demographic characteristics of TCGA samples.

LN-negative LN-postive p
N 128 115
Race (%) 0.355
   NA 3 (2.3) 0 (0.0)
   American Indian or Alaska native 0 (0.0) 1 (0.9)
   Asian 6 (4.7) 5 (4.3)
   Black or African American 23 (18.0) 17 (14.8)
   White 96 (75.0) 92 (80.0)
Number of positive lymphnodes by HE (mean (sd)) 0.00 (0.00) 7.13 (5.71) <0.001
Progesterone receptor status (%) 0.035
   NA 9 (7.0) 10 (8.7)
   Indeterminate 0 (0.0) 1 (0.9)
   Negative 54 (42.2) 29 (25.2)
   Positive 65 (50.8) 75 (65.2)
Estrogen receptor status (%) 0.01
   NA 8 (6.2) 10 (8.7)
   Indeterminate 0 (0.0) 1 (0.9)
   Negative 46 (35.9) 20 (17.4)
   Positive 74 (57.8) 84 (73.0)
HER2 immunohistochemistry receptor status (%) 0.026
   NA 15 (11.7) 26 (22.6)
   Equivocal 28 (21.9) 12 (10.4)
   Indeterminate 0 (0.0) 1 (0.9)
   Negative 69 (53.9) 57 (49.6)
   Positive 16 (12.5) 19 (16.5)
Therapy types (%) 0.019
   NA 36 (28.1) 24 (20.9)
   Ancillary 1 (0.8) 1 (0.9)
   Chemotherapy 55 (43.0) 73 (63.5)
   Chemotherapy and hormone therapy 0 (0.0) 1 (0.9)
   Hormone therapy 34 (26.6) 12 (10.4)
   Immunotherapy 1 (0.8) 1 (0.9)
   Targeted molecular therapy 0 (0.0) 1 (0.9)
   Other 1 (0.8) 2 (1.7)
Pathologic stage (%) <0.001
   Stage II 3 (2.4) 1 (0.9)
   Stage IIA 106 (82.8) 8 (7.0)
   Stage IIB 15 (11.7) 26 (22.6)
   Stage III 0 (0.0) 2 (1.7)
   Stage IIIA 0 (0.0) 53 (46.1)
   Stage IIIB 4 (3.1) 3 (2.6)
   Stage IIIC 0 (0.0) 22 (19.1)
Age at initial pathologic diagnosis (mean (sd)) 54.87 (9.19) 52.43 (9.08) 0.039
Vital status follow up (%) 0.142
   NA 2 (1.7) 3 (2.8)
   Alive 111 (91.7) 89 (83.2)
   Dead 8 (6.6) 15 (14.0)
   OS time (mean (sd)) 1108.70 (1069.91) 1416.06 (1426.87) 0.091