Table 1.
Demographic characteristics of TCGA samples.
LN-negative | LN-postive | p | |
---|---|---|---|
N | 128 | 115 | |
Race (%) | 0.355 | ||
NA | 3 (2.3) | 0 (0.0) | |
American Indian or Alaska native | 0 (0.0) | 1 (0.9) | |
Asian | 6 (4.7) | 5 (4.3) | |
Black or African American | 23 (18.0) | 17 (14.8) | |
White | 96 (75.0) | 92 (80.0) | |
Number of positive lymphnodes by HE (mean (sd)) | 0.00 (0.00) | 7.13 (5.71) | <0.001 |
Progesterone receptor status (%) | 0.035 | ||
NA | 9 (7.0) | 10 (8.7) | |
Indeterminate | 0 (0.0) | 1 (0.9) | |
Negative | 54 (42.2) | 29 (25.2) | |
Positive | 65 (50.8) | 75 (65.2) | |
Estrogen receptor status (%) | 0.01 | ||
NA | 8 (6.2) | 10 (8.7) | |
Indeterminate | 0 (0.0) | 1 (0.9) | |
Negative | 46 (35.9) | 20 (17.4) | |
Positive | 74 (57.8) | 84 (73.0) | |
HER2 immunohistochemistry receptor status (%) | 0.026 | ||
NA | 15 (11.7) | 26 (22.6) | |
Equivocal | 28 (21.9) | 12 (10.4) | |
Indeterminate | 0 (0.0) | 1 (0.9) | |
Negative | 69 (53.9) | 57 (49.6) | |
Positive | 16 (12.5) | 19 (16.5) | |
Therapy types (%) | 0.019 | ||
NA | 36 (28.1) | 24 (20.9) | |
Ancillary | 1 (0.8) | 1 (0.9) | |
Chemotherapy | 55 (43.0) | 73 (63.5) | |
Chemotherapy and hormone therapy | 0 (0.0) | 1 (0.9) | |
Hormone therapy | 34 (26.6) | 12 (10.4) | |
Immunotherapy | 1 (0.8) | 1 (0.9) | |
Targeted molecular therapy | 0 (0.0) | 1 (0.9) | |
Other | 1 (0.8) | 2 (1.7) | |
Pathologic stage (%) | <0.001 | ||
Stage II | 3 (2.4) | 1 (0.9) | |
Stage IIA | 106 (82.8) | 8 (7.0) | |
Stage IIB | 15 (11.7) | 26 (22.6) | |
Stage III | 0 (0.0) | 2 (1.7) | |
Stage IIIA | 0 (0.0) | 53 (46.1) | |
Stage IIIB | 4 (3.1) | 3 (2.6) | |
Stage IIIC | 0 (0.0) | 22 (19.1) | |
Age at initial pathologic diagnosis (mean (sd)) | 54.87 (9.19) | 52.43 (9.08) | 0.039 |
Vital status follow up (%) | 0.142 | ||
NA | 2 (1.7) | 3 (2.8) | |
Alive | 111 (91.7) | 89 (83.2) | |
Dead | 8 (6.6) | 15 (14.0) | |
OS time (mean (sd)) | 1108.70 (1069.91) | 1416.06 (1426.87) | 0.091 |