Table 4.
Logistic Regression Analysis Examining Proteins relation to Prevalent Diabetes
| OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | |
|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | ||||
| PAI | 1.35 (1.22–1.50) | 2.0 × 10−8 | 1.00 (0.89–1.13) | 0.984 | 0.80 (0.67–0.95) | 0.012 |
| FABP4 | 1.61 (1.44–1.81) | 3.6 × 10−16 | 1.16 (1.01–1.34) | 0.049 | 1.02 (0.82–1.27) | 0.847 |
| CD163 | 1.58 (1.40–1.78) | 8.3 × 10−14 | 1.35 (1.20–1.52) | 3.5 × 10−7 | 1.17 (0.99–1.38) | 0.061 |
| Gal4 | 1.97 (1.76–2.22) | 6.8 × 10−30 | 1.85 (1.63–2.10) | 1.7 × 10−21 | 1.54 (1.29–1.84) | 1.0 × 10−6 |
| PON3 | 0.59 (0.53–0.66) | 1.7 × 10−21 | 0.78 (0.45–1.35) | 6.6 × 10−5 | 0.94 (0.79–1.12) | 0.495 |
| IGFBP2 | 0.60 (0.54–0.67) | 4.2 × 10−20 | 0.77 (0.68–0.88) | 1.1 × 10−4 | 1.04 (0.86–1.26) | 0.672 |
| CTSD | 1.73 (1.55–1.92) | 1.4 × 10−23 | 1.46 (1.30–1.65) | 2.3 × 10−10 | 1.14 (0.96–1.35) | 0.140 |
Logistic regressions for prevalent diabetes (681 cases in the MPP) adjusted for age and sex (Model 1) and age, sex, BMI, SBP, HT, TG, HDL, physical activity and cystatin C (Model 2) and age, sex, BMI, SBP, HT, TG, HDL, physical activity, cystatin C and FPG (Model 3). PAI; Plasminogen activator inhibitor 1, FABP4; fatty acid binding protein, CD163; scavenger receptor cysteine rich type 1 protein M130, Gal-4; Galectin-4, PON 3; Paraoxonase, IGFBP-2; Insulin-like growth factor-binding protein 2, CTSD; Cathepsin D.