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. 2019 Jan 22;9:284. doi: 10.1038/s41598-018-36489-8

Figure 5.

Figure 5

Setdb2 expression in IAE model mice. (a) The gene expressions of 84 epigenetic chromatin modification enzymes in whole brains from the IAE group at 8 h post LPS administration were analysed by PCR array. The fold regulation threshold was 3. (b) Gene expression of Setdb2 in whole brains at 8 h and 24 h post LPS administration. Data are shown as the mean ± SEM (8 h control, n = 5; Flu, n = 3; LPS, n = 5; Flu + LPS, n = 5; 24 h control, n = 5; Flu, n = 5; LPS, n = 3; Flu + LPS, n = 6) and are from a representative experiment of two or three independent experiments. *p < 0.05; ***p < 0.001. (c) Gene expression of Setdb2 at 8 h and 24 h post LPS administration in BVECs. Data are shown as the mean ± SEM (8 h control, n = 4; Flu, n = 4; LPS, n = 4; Flu + LPS, n = 4; 24 h control, n = 3; Flu, n = 3; LPS, n = 3; Flu + LPS, n = 3) and are from a representative experiment of two or three independent experiments. **p < 0.01; ***p < 0.001.