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. 2019 Jan 22;9:286. doi: 10.1038/s41598-018-36362-8

Table 3.

Univariate and multivariate analysis of overall survival and disease-free survival.

Factors Univariate analysis Multivariate analysis
HR (95% CI) p value HR (95% CI) p value
OS
Age <35, 35~60, >60 1.343 (0.745–2.424) 0.327 2.737 (1.350–5.551) 0.005
Pathology IMPC, IDC 0.905 (0.487–1.683) 0.752 0.727 (0.358–1.478) 0.379
TNM stage I, II, III 3.590 (1.952–6.603) <0.001 2.822 (1.362–5.850) 0.005
LVIa Negative, positive 2.934 (1.133–7.601) 0.027 1.575 (0.528–4.696) 0.415
HRb status Negative, positive 0.361 (0.176–0.738) 0.005 0.277 (0.106–0.722) 0.009
HER2c status Negative, positive 1.083 (0.529–2.218) 0.827 0.833 (0.331–2.092) 0.697
DFS
Age <35, 35~60, >60 0.676 (0.457–1.001) 0.051 0.888 (0.564–1.397) 0.606
Pathology IMPC, IDC 0.901 (0.601–1.352) 0.616 0.944 (0.601–1.481) 0.802
TNM stage I, II, III 3.082 (2.155–4.408) <0.001 2.665 (1.731–4.103) <0.001
LVI Negative, positive 2.053 (1.204–3.502) 0.008 0.960 (0.513–1.799) 0.900
HR status Negative, positive 0.786 (0.429–1.441) 0.437 1.059 (0.517–2.167) 0.876
HER2 status Negative, positive 1.554 (1.007–2.399) 0.046 1.314 (0.798–2.166) 0.284

LVIa: lymphovascular invasion.

HRb: hormone receptor.

HER2c: epidermal growth factor receptor 2.