Table 1.

Semi-quantitative analysis of the cellular features.

		T1	T3	T5	T10
C	Epithelial cell advancement front	0	+	++	+++
	Multi-layered re-epithelialization	0	+	+	+++
	Ki-67-positive nuclei	0	+	++	++
	Lymph-plasma-cell infiltration	+	+	+	++
	Fibroblast infiltration	+	+	+	++
	Vascularization	+	+	++	+++
D	Epithelial cell advancement front	+	++	+++	+++
	Multi-layered re-epithelialization	0	++	+	+++
	Ki-67-positive nuclei	+	+++	+++	0
	Lymph-plasma-cell infiltration	+	++	+++	+++
	Fibroblast infiltration	++	++	+	++
	Vascularization	+	++	+++	+++
DP	Epithelial cell advancement front	0	++	+++	+++
	Multi-layered re-epithelialization	0	+	++	+++
	Ki-67-positive nuclei	+	++	+++	++
	Lymph-plasma-cell infiltration	+	++	++	+
	Fibroblast infiltration	++	+	++	+
	Vascularization	+	++	+++	+++

Epithelial cell advancement front: 0 = absent, + = initial, ++ = advanced, +++ = complete;

Multi-layered re-epithelialization: 0 = absent, + = low, ++ = good, +++ = mature;

Ki-67-positive nuclei: 0 = absent, + = present at the margins, ++ = diffuse, +++ = abundant;

Lymph-plasma-cell infiltration: + = minimum, ++ = moderate, +++ = abundant;

Fibroblast infiltration: + = minimum, ++ = moderate, +++ = abundant;

Vascularization: + = poor, ++ = discrete, +++ = abundant.