Table 4.
Unadjusted odds ratios and corresponding 95% confidence intervals on the intergenerational effect of depressive disorder in three generationsa
| OR (95% Ci) | ||
|---|---|---|
| Cohort 1, 1973–1977 | Cohort 2, 1978–1982 | |
| OR Mother diagnosed with MDD | ||
| Grandmother diagnosed with MDD | 2.13 (2.02–2.25) | 2.35 (2.23–2.47) |
| Grandmother not diagnosed with an MDD | Reference | Reference |
| OR child has in-patient careb | ||
| Grandmother or mother diagnosed with MDD | 2.23 (2.03–2.45) | 2.10 (1.88–2.34) |
| Only mother diagnosed with MDD | 1.79 (1.73–1.86) | 1.72 (1.65–1.80) |
| Only grandmother diagnosed with MDD | 1.18 (1.14–1.23) | 1.22 (1.15–1.29) |
| None diagnosed with MDD | Reference | Reference |
| OR child has out-patient carec | ||
| Mother and grandmother diagnosed with MDD | 1.99 (1.82–2.18) | 2.30 (2.08–2.55) |
| Only mother diagnosed with MDD | 1.78 /1.72–1.83) | 1.87 (2.89–1.95) |
| Only grandmother diagnosed with MDD | 1.19 (1.14–1.24) | 1.27 (1.20–1.33) |
| None diagnosed with MDD | Reference | Reference |
| OR child diagnosed with MDD | ||
| Mother and grandmother diagnosed with MDD | 5.07 (4.06–6.34) | 7.20 (4.41–11.77) |
| Only mother diagnosed with MDD | 4.15 (3.72–4.63) | 6.03 (4.58–7.94) |
| Only grandmother diagnosed with MDD | 1.68 (1.43–1.97) | 2.63 (1.78–3.87) |
| None diagnosed with MDD | Reference | Reference |
MDD, major depressive disorder.
a.
All women were born between 1973 and 1982. All children were born between 1987 and 2012. All mothers were born between 1924 and 1978.
b.
In-patient care categorised into 0–1 visits and ≥2 visits.
c.
Out-patient care categorised into 0–10 visits and ≥11 visits.