Table 5.
Adjusted odds ratios and corresponding 95% confidence intervals on the intergenerational effect of depressive disorder in three generationsa
| OR (95% CI) | ||
|---|---|---|
| Cohort 1, 1973–1977 | Cohort 2, 1978–1982 | |
| OR (95% CI) | OR (95% CI) | |
| OR Mother diagnoses with MDD | ||
| Grandmother diagnosed with MDD | 1.91 (1.78–2.04) | 2.12 (1.97–2.27) |
| Grandmother not diagnosed with an MDD | Reference | Reference |
| OR child has in-patient careb | ||
| Mother and grandmother diagnosed with MDD | 1.74 (1.58–1.91) | 1.67 (1.49–1.86) |
| Only mother diagnosed with MDD | 1.53 (1.48–1.59) | 1.50 (1.43–1.57) |
| Only grandmother diagnosed with MDD | 1.10 (1.06–1.15) | 1.11 (1.05–1.18) |
| None diagnosed with MDD | Reference | Reference |
| OR child has out-patient carec | ||
| Mother and grandmother diagnosed with MDD | 1.66 (1.51–1.82) | 1.78 (1.60–1.98) |
| Only mother diagnosed with MDD | 1.60 (1.54–1.65) | 1.58 (1.51–1.65) |
| Only grandmother diagnosed with MDD | 1.13 (1.08–1.17) | 1.12 (1.07–1.19) |
| None diagnosed with MDD | Reference | Reference |
| OR child diagnosed with MDD | ||
| Grandmother and mother diagnosed with MDD | 2.17 (1.60–2.95) | 3.00 (1.64–5.49) |
| Only mother diagnosed with MDD | 2.46 (2.18–2.78) | 2.91 (2.18–3.90) |
| Only grandmother diagnosed with MDD | 1.32 (1.10–1.59) | 1.30 (0.81–2.07) |
| None diagnosed with MDD | Reference | Reference |
a.
All women were born between 1973 and 1982. All children were born between 1987 and 2012. All mothers were born between 1924 and 1978.
b.
In-patient care categorised into 0–1 visits and ≥2 visits.
c.
Out-patient care categorised into 0–10 visits and ≥11 visits.