Table 6.
Unadjusted odds ratios and corresponding 95% confidence intervals on the intergenerational effect of depression in three generations, stratified by age of the child (third generation)
| OR child diagnosed with MDD | Cohort 1 | Cohort 2 | ||
|---|---|---|---|---|
| 0–12 years (n = 324 000) |
≥13 years (n = 57 953) |
0–12 years (n = 232 926) |
≥13 years (n = 5699 |
|
| Mother and grandmother diagnosed with MDD | 1.90 (1.68–2.14) | 1.96 (1.68–2.28) | 2.00 (1.78–2.24) | 1.85 (1.29–2.63) |
| Only mother diagnosed with MDD | 1.60 (1.53–1.67) | 1.66 (1.57–1.77) | 1.66 (1.58–1.74) | 1.54 (1.31–1.81) |
| Only grandmother diagnosed with MDD | 1.12 (1.07–1.18) | 1.15 (1.07–1.24) | 1.19 (1.12–1.26) | 1.22 (0.98–1.52) |
| None diagnosed with MDD | Reference | Reference | Reference | Reference |
MDD, major depressive disorder.