Figure 4.

LV SERCA2a and phosphorylation of troponin I (TnI) in mice with HF 5 weeks after UCn3 gene transfer. (A) LV SERCA2a content was higher in mice with HF that received UCn3 gene transfer (p = 0.0004 vs. HF). (B) Troponin I (TnI) phosphorylation at serine 23 and 24 was higher in HF mice that received UCn3 gene transfer (p = 0.04 vs. HF). Individual mouse data are shown (mean ± SE are indicated); Con, sham-operated animals. p-Values are from a Student's t-test (unpaired, two-tailed) with Bonferroni correction for multiple comparisons. Color images available online at www.liebertpub.com/hum