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. 2019 Jan 10;35(1):63–74. doi: 10.1089/aid.2018.0132

FIG. 2.

FIG. 2.

Increased frequency of nonclassical monocytes correlates with elevated RVSP in SIV-PAH. (A1–3) Total monocyte counts, determined by a blood differential, did not change throughout SIV-infection and were not associated with PAH. (B) Nonclassical monocyte (CD14dimCD16+) counts and (C) classical monocyte (CD14+CD16−) counts were calculated based on the blood differential. (B1) Nonclassical monocytes levels did not change over time. (B2) At 6 mpi PAH+ animals had increased nonclassical monocyte counts over PAH−, which (B3) correlated with elevated RVSP. (C1) Classical monocytes levels increased at 6 mpi, but they were not associated with PAH (C2–3). PAH, pulmonary arterial hypertension; RVSP, right ventricular systolic pressure.