Figure 1.

Oxygen consumption rates (OCRs) in placentas from lean (LN) and obese (OB) women. Representative OCR versus time trace in syncytiotrophoblasts from the placenta of a LN woman (A) following injection of oligomycin, carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone (FCCP), rotenone, and antimycin A. Basal respiration, adenosine triphosphate (ATP)-coupled respiration, proton leak, maximal respiration, spare capacity, and nonmitochondrial respiration in placentas from LN and OB women (B). Oxygen consumption rate was normalized to total cellular protein. Values are mean ± standard error of the mean (SEM); #: P < .05 versus LN; ⁁: P < .01 versus LN; *: P < .001 versus LN; n = 6 LN and 12 OB.